实用医学杂志2016，Vol.32Issue(19)：3117-3119,3.DOI:10.3969/j.issn.1006-5725.2016.19.001
妊娠期慢性乙型肝炎病毒携带者病毒载量与妊娠期糖尿病的相关性
Association between viral load and gestational diabetes mellitus in women with chronic hepatitis B
摘要
Abstract
Objective To analyze the GDM of 336 cases with chronic HBV in pregnancy. Methods According to HBV DNA≥1.0 × 103 IU/mL, participants were divided into HBV DNA (+) or (-) group. 409 cases without HBV were selected as control group. Differences on GMD incidence between groups and virus load and OGTT blood sugar correlation were compared. Results The incidence of GDM of HBV DNA (+) or (-) group was 16.77% and 17.71%, which is higher than that in HBV group (10.27%). The difference is significant (P < 0.05). The correlation index between HBV DNA and fasting blood-glucose is r = 0.005, P = 0.610, the result of which is not statistically significant. But correlation index between HBV DNA and blood sugar at 1 h , 2 h are r = 0.082, 0.086; P = 0.000, 0.000, the result of which is statistically significant. Conclusion The oc-currence of GDM were higher in HBV DNA (+) or (-) group. The viral load is positively related with blood sugar of glucose tolerance at 1 h or 2 h.关键词
乙型肝炎/孕妇/病毒载量/妊娠期糖尿病Key words
Chronichepatitits B/Pregnant women/Viral load/Gestational diabetes mellitus引用本文复制引用
李飞凤,高云飞,黄启涛,黄晨,周元平,刘志华,曾文娟,王海臻,袁国盛,钟梅..妊娠期慢性乙型肝炎病毒携带者病毒载量与妊娠期糖尿病的相关性[J].实用医学杂志,2016,32(19):3117-3119,3.基金项目
国家自然科学青年基金（编号81401208）；广东省医学科研基金 （）
