实用医学杂志2016，Vol.32Issue(19)：3127-3129,3.DOI:10.3969/j.issn.1006-5725.2016.19.004
妊娠前半期甲状腺功能异常与妊娠期糖尿病的临床研究
Study of thyroid dysfunction in the first half of pregnancy and gestational diabetes mellitus
摘要
Abstract
Objective To explore the influence of thyroid dysfunction in the first half pregnancy (≤20 gestational weeks) on gestational diabetes. Methords By adopting the method of prospective intervention study, general data of pregnant-women in the care clinics of our hospital were collected. Thyroid function was detected and evaluated by ATA criteria. All cases were divided into two groups: normal thyroid function group and thyroid dysfunction group. The thyroid dysfunction group was intervened. 75 g OGTT were conducted in all cases in 24-28 gestational-weeks. GDM was diagnosed by IADPSG diagnostic criteria. GDM prevalence was compared between normal thyroid function group and abnormal thyroid function groups. Results 1 062 cases of pregnant women were collected. 857 cases of pregnant women were normal, while 14 cases were subclinical hyperthyroidism (1.32%), 164 cases were subclinical hypothyroidism (15.4%), 22 cases were hypothyroxinemia (2.07%). Compared with normal thyroid function, prevalence rate of GDM was the highest in hypothyroxinemia group (54.5% vs 27.8%). There was no significant difference between subclinical hypothyroidism group and normal thyroid function group. Conclusion Thyroid dysfunction in the first half pregnancy is associated with GDM , Screening and treatment of pregnant thyroid dysfunction should be attached.关键词
甲功异常/妊娠糖尿病Key words
Thyroid dysfunction/Gestational diabetes引用本文复制引用
李利平,姜宏卫,付留俊,袁园,宋白利,秦贵军..妊娠前半期甲状腺功能异常与妊娠期糖尿病的临床研究[J].实用医学杂志,2016,32(19):3127-3129,3.基金项目
洛阳市青年医学科技创新联合资金项目 （）
