实用医学杂志2016，Vol.32Issue(20)：3312-3314,3.DOI:10.3969/j.issn.1006-5725.2016.20.008
维格列汀联合阿卡波糖治疗2型糖尿病的疗效及安全性
The efficacy and safety of vidldagliptin combined with acarbose in treating type 2 diabetes
摘要
Abstract
Objective To observe the efficacy and safety of vildagliptin combined with acarbose in treating type 2 diabetes. Methods 78 patients with type 2 diabetes were divided into two groups to have additional vildagliptin combined with acarbose or acarbose combined with placebo. The clinical efficacy and adverse reactions after 12 weeks were investigated. Results In the treatment group, FBG, 2 h PG and HbA1C declined after treatment (P < 0.05) and FCP, 2 h CP, FINS and 2 h INS increased (P < 0.05). Compared with the control group, FBG and HbA1c in the treatment group were reduced and owever, FCP, 2 h CP, FINS and 2 h INS were increased more significantly (P < 0.05). There was no difference in the incidence of overall BMI between the two groups (P > 0.05). There were either liver and kidney damage (P > 0.05), nor hypoglycemia. Conclusion Vildagliptin combined with acarbose is superior to Acarbose combined with placebo , and it produced no more untoward effect.关键词
2型糖尿病/维格列汀/阿卡波糖/疗效Key words
Type 2 diabetes/Vildagliptin/Acarbose/Curative effect引用本文复制引用
叶儒佳,王光耀,王兴华,孙心怡..维格列汀联合阿卡波糖治疗2型糖尿病的疗效及安全性[J].实用医学杂志,2016,32(20):3312-3314,3.基金项目
江苏省自然科学基金项目（编号BK2012857）；江苏省高校优势学科建设工程项目 （）
