现代妇产科进展2016，Vol.25Issue(10)：766-768,771,4.DOI:10.13283/j.cnki.xdfckjz.2016.10.011
不同分娩方式对乙型肝炎病毒母婴垂直传播的影响
The effect of delivery mode on materal-infant transmission of hepatitis B virus
摘要
Abstract
Objective:To discuss the effect of delivery mode on materal-infant trans-mission of hepatitis B virus. Method:Collect the HbsAg-positive gravidas who take the system-atic antenatal examination and deliver at term in the first affiliated hospital of Jinan University as hepatitis B group,68 cases in totol,and 64 HbsAg-negative cases at the same period as con-trol group. In the hepatitis B group,collect materal venous blood before labor to test HBV-Ms, placental alkaline phosphatase ( PLAP ) and HBV-DNA, cord blood to test PLAP and HBV-DNA,infant venous blood in 24 hours since birth to test HBV-Ms and HBV-DNA. In the control group,collect materal venous blood before labor and cord blood to test PLAP. Result:In both hepatitis B group and control group,selected cesarean section has the lower PLAP in cord blood than vaginal delivery(P<0. 05). In hepatitis B group,HBV-DNA、HBsAg in infant venous blood was all negtive in both two delivery mode,the positive rate of HBeAg has no significant difference(P>0. 05). Conclusion:Selected cesarean section can reduce the penetration from materal blood to infant blood.关键词
乙型肝炎病毒/分娩方式/垂直传播Key words
Hepatitis B/Delivery mode/Vertical transmission分类
医药卫生引用本文复制引用
王绮,李雪,肖小敏..不同分娩方式对乙型肝炎病毒母婴垂直传播的影响[J].现代妇产科进展,2016,25(10):766-768,771,4.基金项目
国家自然科学基金资助项目(No:81370676) （No:81370676）
广东省社会发展科技领域科技计划项目(No:2005B34201010) （No:2005B34201010）
