中国中医药信息杂志2016，Vol.23Issue(11)：22-24,3.DOI:10.3969/j.issn.1005-5304.2016.11.006
柴胡加龙骨牡蛎汤加减方联合心理干预治疗肿瘤后抑郁临床研究
Clinical Study on Combination of Modification ofChaihu Jia Longgu Muli Decoction with Psychological Intervention in Treatment of Post Tumor Depression
摘要
Abstract
Objective To observe the clinical efficacy of the combination of modification ofChaihu Jia Longgu MuliDecoction with psychological intervention in the treatment of post tumor depression.MethodsTotally 122 cases of post tumor depression were divided into treatment group and control group by simple numeration table random method, with 61 cases in each group. The treatment group was given modification ofChaihu Jia Longgu Muli Decoction orally, at the same time psychological intervention was given. The control group was given escitalopram oxalate tablets for 6 weeks. HAMD scale scores of the two groups were observed before and after treatment to evaluate the clinical efficacy. Changes in life quality of two groups were scored with SF-36 scale. The adverse reactions were also observed.ResultsAfter treatment, the HAMD score of treatment group was lower than control group (P<0.05). The total effective rate was 88.52% (54/61) in the treatment group and 72.13% (44/61) in the control group, with statistical significance (P<0.05). The scores of life quality of treatment group were higher than control group (P<0.05), and the incidence of adverse reactions was lower than control group (P<0.05).Conclusion Combination of modification ofChaihu Jia Longgu MuliDecoction with psychological intervention in the treatment of post tumor depression can significantly improve the depressive state and life quality of the patients with post tumor depression, which is better than the control group, without significant adverse reactions.关键词
柴胡加龙骨牡蛎汤/抑郁症/肿瘤/心理干预Key words
Chaihu Jia Longgu MuliDecoction/depression/tumor/psychological intervention分类
医药卫生引用本文复制引用
王锦辉,王建华,刘洪伟,马莉,陈淑媛,杨俊泉,彭静,韩秀红,刘静..柴胡加龙骨牡蛎汤加减方联合心理干预治疗肿瘤后抑郁临床研究[J].中国中医药信息杂志,2016,23(11):22-24,3.基金项目
河北省中医药管理局科学技术课题 （）
