安徽农业科学2016，Vol.44Issue(28)：130-132,3.
DOP对鲤鱼的遗传毒性及肝脏抗氧化系统的影响
Effects of DOP on the Genetic Toxicity and Liver Antioxidant System in Carps
摘要
Abstract
Objective] To study the effects of DOP on the genetic toxicity and oxidation resistance of carps,and to provide theoretical basis for evaluating the biological toxicity and ecological risk to water environments of DOP.[Method] The effects of exposing with DOP (0.3,1.5,7.5 mg/L) for 24 h on erythrocyte nuclei abnormal rate and activities of liver SOD and POD and the content of MDA by Giemsa staining and the kit method.[ Result] In the experimental concentration range of DOP,rate of micronucleus,nuclear anomalies and total nuclear anomaly on the eryth-rocyte were increased with the increase of DOP concentration,and the rate of micronucleus in the 7.5 mg/L DOP group was significantly higher than that in the control group.SOD activity was promoted in Low concentration and inhibited in high concentration.POD activity at 0.3 mg/L group was significantly higher,but it had no significant change at 1.5 and 7.5 mg/L DOP group compared with the control group.The content of MDA was increased with the increase of DOP concentration,and that in each DOP group was significantly higher than the control group.[ Conclu-sion] A certain concentration of DOP has a genetic toxicity and can damage the antioxidant defense system of fish.关键词
邻苯二甲酸二辛酯/鲤鱼/微核/核异常/超氧化物歧化酶/过氧化物酶/丙二醛Key words
Dioctyl Phthalate(DOP)/Cyprinus carpio Linnaeus(Carp)/Micronucleus/Nuclear anomalies/SOD/POD/MDA分类
农业科技引用本文复制引用
李凤芝..DOP对鲤鱼的遗传毒性及肝脏抗氧化系统的影响[J].安徽农业科学,2016,44(28):130-132,3.基金项目
山东省自然科学基金项目（ ZR2010CM046）。 （）
