动物营养学报2016，Vol.28Issue(10)：3064-3069,6.DOI:10.3969/j.issn.1006-267x.2016.10.007
丁酸对乳腺组织基因表达的调控作用及其机制
Regulatory Functions and Mechanism of Butyrate on Gene Expressions in Mammary Glands
摘要
Abstract
Butyrate, as one of the most important kinds of short chain fatty acids, plays some important physi-ological roles as a signal molecule and its receptor, for regulate lipid metabolism in the mammary gland, liver and fatty tissue. The mechanism of butyric acid is multifaceted and its involvement in the regulation of gene ex-pression. Butyric acids not only regulate the expression of a particular gene, but also involved in the regulation of signaling pathways and gene networks. This paper reviewed the regulatory functions of butyrate in the mam-mary tissue and its mechanism as a precursor of milk fat, histonede acetylase ( DHAC) inhibitors and the lig-and of G-protein coupled receptors on gene expressions.关键词
丁酸/乳脂合成前体物/组蛋白去乙酰酶抑制剂/G蛋白偶联受体的配体/机制Key words
butyrate/milk fat precursors/histone deacetylase inhibitors/the ligand of G-protein coupled re-ceptors/mechanism分类
农业科技引用本文复制引用
邢媛媛,李大彪,塔娜,李红磊..丁酸对乳腺组织基因表达的调控作用及其机制[J].动物营养学报,2016,28(10):3064-3069,6.基金项目
国家自然科学基金(31360559) （31360559）
内蒙古自治区高等学校“青年科技英才支持计划”(NJYT-14-B05) （NJYT-14-B05）
