生物信息学2016，Vol.14Issue(3)：181-187,7.DOI:10.3969/j.issn.1672-5565.2016.03.09
蛋白质二级结构指定
Protein secondary structure assignment
曹晨 1马堃2
作者信息
- 1. 吉林大学计算机科学与技术学院，长春130012
- 2. 江苏恒瑞医药股份有限公司，江苏连云港222047
- 折叠
摘要
Abstract
Secondary structure protein refers to regular repeative sub-structures on the protein backbone.The accurate assignment of the secondary structure of proteins from protein atom coordinates underlies the analysis of protein structure and function.It is also very important for protein classification, finding functional motifs in proteins, and understanding the folding mechanisms of proteins as well as for molecular visualization, protein comparison and prediction.Thus, protein secondary structure assignment is still an active research field in structural bioinformatics.More than twenty secondary structure assignment methods have been developed and are generally categorized into two groups, i.e.,geometry-based and hydrogen bond-based.However, the consistence of secondary structure assigned by different methods is relatively low.These is no review paper about protein secondary structure assignment so far.Therefore,this paper mainly introduce and summarize these methods.关键词
蛋白质二级结构指定/蛋白质结构Key words
Protein secondary structure assignment/Protein structure分类
生物科学引用本文复制引用
曹晨,马堃..蛋白质二级结构指定[J].生物信息学,2016,14(3):181-187,7.
