烟草科技2016，Vol.49Issue(10)：36-43,8.DOI:10.16135/j.issn1002-0861.2015.0680
光电离质谱法测定卷烟烟气中有害成分的口腔残留
Determination of buccal residues of harmful components from cigarette smoke by photoionization mass spectrometry
摘要
Abstract
In order to determine the human buccal residues of harmful components from cigarette smoke, an on-line measurement system based on ultraviolet photoionization time-of-flight mass spectrometry (VUV-PI-TOFMS) technique was established. The photoionization mass spectra of fresh vapour phase mainstream cigarette smoke generated from a smoking machine directly or retained in the mouth of volunteers for different times were obtained. The retention efficiencies of the main toxic components from cigarette smoke in buccal cavity, such as nitric oxide (mass-charge ratio, m/z=30), acetaldehyde (m/z=44), 1,3-butadiene (m/z=54), acetone (m/z=58), isoprene (m/z=68), benzene (m/z=78), phenol (m/z=94) and ethylbenzene (m/z=106) were analyzed comparatively according to the results of qualitative analysis. The results showed that: 1) When cigarette smoke was retained in mouth for 2 s, the retention efficiencies of buccal cavity for aldehyde and ketone compounds were the highest, followed by phenol; while those for nitric oxide and unsaturated hydrocarbons were relatively lower. 2) Within 26 s, the longer the retention time, the higher the retention efficiencies for aldehyde and ketone compounds; and those for the other compound were also raised rapidly within the first 10-14 s, then nearly kept constant. VUV-PI-TOFMS achieved direct smoke sampling and analysis from both smoking machine and human buccal cavity, and hence is a powerful tool to study the buccal residues of harmful components from cigarette smoke.关键词
光电离质谱/卷烟烟气/气相物/有害成分/口腔残留Key words
Photoionization mass spectrometry/Cigarette smoke/Vapour phase matter/Harmful component/Buccal residue分类
轻工纺织引用本文复制引用
王健,胡永华,张晓宇,徐迎波,王程辉,田振峰..光电离质谱法测定卷烟烟气中有害成分的口腔残留[J].烟草科技,2016,49(10):36-43,8.基金项目
安徽中烟工业有限责任公司博士后科研基金资助项目“卷烟及电子烟主流烟气化学成分在人体口腔中残留研究”（2015101）和科技计划资助项目“应用光电离质谱技术在线研究单口卷烟烟气气相化学成分”（2016116）。 （）
