中国输血杂志2016，Vol.29Issue(8)：820-822,3.DOI:10.13303/j.cjbt.issn.1004-549x.2016.08.013
血栓弹力图在检测血小板减少孕妇凝血功能中的应用
Application of thrombelastogram in the determination of coagulation function during pregnancy
黄吉娥 1涂飞 1杨芳 2曾小菁 1祝丽丽 1赵鲁强1
作者信息
- 1. 贵州医科大学附属医院,贵州贵阳550004
- 2. 贵州医科大学
- 折叠
摘要
Abstract
Objective To utilize the thrombelastogram (TEG) to evaluate coagulation function during pregnancy and to predict the potential risk of hemorrhage during delivery.Methods Forty two pregnant women with thrombocytopenia,including 20 with Plt ＜50 × 109/L (group Ⅰ) and 22 with Plt (50-100) × 109/L (group Ⅱ) and 30 normal pregnant with Plt (100-300 × 109/L) (group Ⅲ) were measured and analyzed on reaction time (R),clotting time (K),α angle,maximum amplitude (MA) and coagulation index (CI).Simultaneously,the PT,APTT,TT,Fg in above samples were determined with a freezing method (magnetic beads method) and the Plt count was recorded using the light scattering method.Results Compared with group Ⅰ,significant difference (P ＜ 0.05) was observed in MA and Fg.Significant difference (P ＜ 0.05) was also observed in K,α angle and CI between groups Ⅰ and Ⅲ,but no significant difference was observed between groups Ⅰ and Ⅱ.In addition,the parameters according to the TEG is divided into groups A,B,C which were studied.From the correlation of MA,K and CI with the amount of hemorrhage,a significant difference in the amount of blood loss (≥800mL or ＜800 mL) was found between groups A and group C,and groups B and C,respectively (P ＜0.05).Conclusion TEG could be used as a useful indicator to monitor blood coagulation in pregnant women with thrombocytopenia.When the parameters are low to a certain limit,the amount of bleeding and the rate of mortality increase significantly.关键词
血栓弹力图/妊娠/血小板减少/出血Key words
thrombelastogram/pregnant/thrombocytopenia/bleeding分类
临床医学引用本文复制引用
黄吉娥,涂飞,杨芳,曾小菁,祝丽丽,赵鲁强..血栓弹力图在检测血小板减少孕妇凝血功能中的应用[J].中国输血杂志,2016,29(8):820-822,3.
