摘要
Abstract
Objective:To explore the clinical efficacy and value of Benazepril combined with Piperazine Ferulate Tablets in the treatment of chronic glomerulonephritis.Method:From December 2013 to December 2015,180 cases of clearly diagnosed to suffer from primary chronic glomerulonephritis in our hospital were selected as the research objects,they were divided into the control group of 92 cases and the observation group of 88 cases according to the random number table method.The control group was given oral Benazepril Hydrochloride Tablets therapy and the observation group was given Benazepril Hydrochloride Tablets combined with Piperazine Ferulate Tablets therapy,4 weeks for 1 courses of treatment and two groups were continuous treatment of 4 courses.The blood pressure,24 h urine protein quantity before and after treatment and total effective rate of two groups were observed and compared.Result:Before treatment,the blood pressure in the control group was (139±12)/(78±7) mm Hg and that of the observation group was(138±11)/(80±9) mm Hg,the difference was not statistically significant(P>0.05).After treatment,the blood pressure in the control group was (136±10)/(76±7) mm Hg and that of the observation group was(135±10)/(78±8) mm Hg,the blood pressure in two groups was lower than before treatment,but there was no significant difference,and there was no significant difference of two groups(P>0.05).Before treatment,the urine protein quantitative within 24 h in the control group was(1.87±0.62)g,while that of the observation group was(1.92±0.67)g,the difference was not statistically significant(P>0.05).After treatment,the urine protein quantitative within 24 h in the control group was (0.89±0.45)g,while that of the observation group was(0.61±0.41)g,the urine protein quantitative within 24 h in two groups were significantly lower than that of before treatment(P<0.05),and the the urine protein quantitative within 24 h in the observation group after treatment was significantly lower thanthat of the control group(P<0.05).The total effective rate in the observation group was 94.32%,higher than 78.26% of the control group,the difference was statistically significant(P<0.05).Conclusions:Benazepril Hydrochloride Tablets combined with Piperazine Ferulate Tablets has obvious effects in the treatment of chronic glomerulonephritis for reducing the urine protein and improving the effective rate.关键词
盐酸贝那普利片/保肾康/慢性肾小球肾炎/临床疗效/价值Key words
Benazepril Hydrochloride Tablets/Piperazine Ferulate Tablets/Chronic Glomerulonephritis/Clinical efficacy/Value
