摘要
Abstract
Objective:To evaluate the incidence and risk factors of upper-extremity deep vein thrombosis (UEDVT) related to peripherally inserted central venous catheter in cancer patients.Method:From June 2014 to November 2014,177 cases of solid tumor patients who underwent implantation of a peripherally inserted central venous catheter were selected in our hospital.All patients were examined at prescribed intervals by ultrasonography (US) to estimate the incidence of catheter-related venous thrombosis.Result:During the study period,177 PICC were placed in 177 cases of patients followed up for a total of 15 115 catheter-days,the mean duration of catheter was 85.4 d.The incidence rate of cancer patients with PICC-UEDVT was 25.42%, of which the incidence of symptomatic usm - UEDVT was 5.08%.In adjusted by Logistic analysis,distant metastasis[OR=8.537,95%CI (2.447,29.781),P=0.001],Fibrinogen>2.0 g/L[OR=6.578,95%CI(2.076,20.845),P=0.001],D-Dimer>2.0 ng/L[OR=4.873,95%CI(1.482,16.025),P=0.009],infection[OR=6.069,95%CI(1.789,20.589),P=0.004] were factors influencing the risk of DVT,the differences were statistically significant(P<0.05).Conclusion:The incidence of PICC-UEDVT in cancer patients is 25.42% and symptomatic PICC-UEDVT is 5.08%.Cancer patient with distant metastasis,Fibrinogen>2.0 g/L,D-Dimer>2.0 ng/L,infection increase the risk of PICC-UEDVT.关键词
肿瘤/PICC/上肢深静脉血栓形成Key words
Cancer/Peripherally inserted central venous catheter/Upper-extremity deep vein thrombosis