口腔疾病防治2016，Vol.24Issue(11)：640-644,5.DOI:10.12016/j.issn.2096-1456.2016.11.004
外源性右旋糖酐酶和氟化钠对粘性放线菌生物膜的影响
Effects of exogenous dextranase and sodium fluoride on Actinomyces viscosus biofilm
摘要
Abstract
[Abstact] Objective To explore the impact of exogenous dextranase (Dex) and sodium fluoride (NaF) on the bio⁃film formation of Actinomyces viscosus. Methods Crystal violet was used to quantify the biomass of Actinomyces visco⁃sus treated with serial concentrations of Dex and NaF. Scanning electronic microscope was applied to detect the mor⁃phology and structure of the biofilms. Results The formation of Actinomyces viscosus biofilm was inhibited when the concentrations of Dex or NaF rised. Compared with the separate use of 0.25 U/mL Dex and 40 or 80 μg/mL NaF, the combined use of these two agents could obviously inhibit the biofilm formation. Conclusion Both separate and com⁃bined use of Dex and NaF could inhibit the Actinomyces viscosus biofilm formation, and they displayed synergistic effect under certain conditions.关键词
右旋糖酐酶/氟化钠/粘性放线菌/生物膜/协同作用Key words
Dextranase/Sodium fluoride/Actinomyces viscosus/Biofilm/Synergistic effect分类
医药卫生引用本文复制引用
田媛媛,喻譞,房宏志,杨英明,杨惠,胡涛..外源性右旋糖酐酶和氟化钠对粘性放线菌生物膜的影响[J].口腔疾病防治,2016,24(11):640-644,5.基金项目
国家自然科学基金（81400507）；四川省科技厅应用基础研究项目 （）
