国际医药卫生导报2016，Vol.22Issue(21)：3237-3239,3.DOI:10.3760/cma.j.issn.1007-1245.2016.21.007
丹参酮ⅡA磺酸钠对造影剂引起肾脏损害的作用
The effect of sodium tanshinone Ⅱ A sulfonate on kidney damage caused by contrast agent
摘要
Abstract
Objective To explore whether sodium tanshinone Ⅱ A sulfonate can effectively improve kidney damage caused by contrast agent or not.Methods 82 patients undergoing coronary angiography in our hospital from January 2014 to June 2015 were selected,and randomly divided into study group (sodium tanshinone Ⅱ A sulfonate treatment) and control group (basic treatment).Compared the changes of renal function of two groups after treatment.Results Glomerular filtration rate showed a decreasing trend on the postoperative first and third day in all patients,glomerular filtration rate in study group on the postoperative seventh and tenth day were significantly higher than those in control group.The level of uric acid decreased from (287.2±23.5) μmol/L to (224.7±29.9)μmol/L in study group,(272.4±28.9)μtmol/L to (265.9±21.1)μmol/L in control group,the level of uric acid in study group after surgery was significantly lower than that in control group.Conclusion Under the guidance of KDIGO guide,proper use of sodium tanshinone Ⅱ A sulfonate can improve kidney damage caused by contrast agent,improve the quality of life of patients.关键词
丹参酮ⅡA磺酸钠/造影剂/肾脏损害Key words
Sodium tanshinone Ⅱ A sulfonate/Contrast agent/Kidney damage引用本文复制引用
钟嘉荣,陆莲,方滨..丹参酮ⅡA磺酸钠对造影剂引起肾脏损害的作用[J].国际医药卫生导报,2016,22(21):3237-3239,3.基金项目
佛山市卫生局医学科研课题(2014001)Medical Scientific Research Subject Supported by Health Bureau of Foshan City (2014001) （2014001）
