海南医学院学报2016，Vol.22Issue(21)：2581-2583,2587,4.DOI:10.13210/j.cnki.jhmu.20160823.012
慢性荨麻疹患者甲状腺激素水平、免疫功能状态与病情的相关性
Correlation of thyroid hormone levels and immune function state with the illness in patients with chronic urticaria
摘要
Abstract
Objective:To study the correlation of thyroid hormone level and immune function state with the illness in patients with chronic urticaria.Methods:A total of 54 patients with chronic urticaria treated in our hospital between May 201 5 and October 201 5 were selected as the chronic urticaria group (CU group)of the study,50 healthy volunteers receiving physi-cal examination in our hospital during the same period were selected as the negative control group (NC group)of the study,se-rum was collected to determine the content of immunoglobulins,complements,interleukins,thyroid hormone and autoantibod-ies.Results:Serum C3,C4 and IL-2 content of CU group were significantly lower than those of NC group while IgG,IgE,IL-4,IL-1 7,IL-18 and IL-33 content were significantly higher than those of NC group;serum TT3,TT4,FT3,FT4,TSAb, TGAb,TPOAb and TMAb content of CU group were significantly higher than those of NC group,negatively correlated with serum C3,C4 and IL-2 content,and positively correlated with serum IgG,IgE,IL-4,IL-1 7,IL-18 and IL-33 content;serum TSH content was significantly lower than that of NC group,positively correlated with serum C3,C4 and IL-2 content,and negatively correlated with serum IgG,IgE,IL-4,IL-1 7,IL-18 and IL-33 content.Conclusions:Thyroid autoantibody synthesis and thyroid hormone release increase in patients with chronic urticaria,and the change of thyroid hormone levels and immune function is closely related to the illness.关键词
慢性荨麻疹/自身抗体/甲状腺激素/TSHKey words
Chronic urticaria/Autoantibody/Thyroid hormone/TSH分类
医药卫生引用本文复制引用
孙晓岩,杨光忠,李庆祥,王瑶..慢性荨麻疹患者甲状腺激素水平、免疫功能状态与病情的相关性[J].海南医学院学报,2016,22(21):2581-2583,2587,4.基金项目
国家自然科学基金(81500164)[Foundation Project]:Natural Science Foundation of China No：81500164． （81500164）
