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子宫内膜异位症患者血清及组织雌孕激素受体、VEGF 及其受体的变化观察

康凌 张春华 宋元梓 宋晓玲 张宁 张德洋

海南医学院学报2016,Vol.22Issue(21):2592-2594,2598,4.
海南医学院学报2016,Vol.22Issue(21):2592-2594,2598,4.DOI:10.13210/j.cnki.jhmu.20160831.024

子宫内膜异位症患者血清及组织雌孕激素受体、VEGF 及其受体的变化观察

Change of serum and tissue estrogen and progesterone receptor,VEGF and its receptors in patients with endometriosis

康凌 1张春华 1宋元梓 1宋晓玲 1张宁 2张德洋3

作者信息

  • 1. 南阳市第二人民医院 妇一科,河南 南阳 473000
  • 2. 南阳市第二人民医院 PCR 实验室,河南 南阳 473000
  • 3. 南阳市第二人民医院 病理科,河南 南阳 473000
  • 折叠

摘要

Abstract

Objective:To study the changes of serum and tissue levels of estrogen receptor,progesterone receptor, VEGF and its receptors in patients with endometriosis.Methods:A total of 60 patients with endometriosis in our hospital from March 201 5 to April 201 6 were selected as the observation group,60 healthy women of the same age at the same period were selected as the control group,then the expression situation of serum and tissue estrogen and progesterone receptor,VEGF and its receptors of two groups were compared,and the expression situation of serum and tissue estrogen and progesterone recep-tor,VEGF and its receptors of observation group with different types and r-AFS stages were compared too.Results:The serum and tissue estrogen and progesterone receptor of observation group were all lower than those of control group,the VEGF and its receptors were all higher than those of control group,and the expression situation of serum and tissue estrogen and proges-terone receptor,VEGF and its receptors of observation group with different r-AFS stages had obvious differences too,all P <0.05,while the serum and tissue estrogen and progesterone receptor,VEGF and its receptors of observation group with differ-ent types had no obvious differences (all P > 0.05 ).Conclusions:The serum and tissue estrogen and progesterone receptor,&nbsp;VEGF and its receptors of patients with endometriosis show abnormal state,and the differences of the indexes expression of patients with different disease stages are obvious,so the indexes detection value are higher.

关键词

子宫内膜异位症/血清/组织/雌孕激素受体/VEGF 及其受体

Key words

Endometriosis/Serum/Tissue/Estrogen and progesterone receptor/VEGF and its receptors

分类

医药卫生

引用本文复制引用

康凌,张春华,宋元梓,宋晓玲,张宁,张德洋..子宫内膜异位症患者血清及组织雌孕激素受体、VEGF 及其受体的变化观察[J].海南医学院学报,2016,22(21):2592-2594,2598,4.

基金项目

河南杰出人才创新基金资助项目(0621354922)[Foundation Project]:It is supported by Excellent Talent Innovation Fund of Henan Province (0621354922). (0621354922)

海南医学院学报

OACSTPCD

1007-1237

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