河北医学2016，Vol.22Issue(10)：1600-1602,3.DOI:10.3969/j.issn.1006-6233.2016.10.007
皮肌炎相关的肺间质病变经激素联合免疫抑制剂治疗后肺功能变化
The Changes of Lung Function of Patients Dermatomyositis Associated Interstitial Lung Disease by Hormone Combined with Immunosuppressive Therapy
摘要
Abstract
Objective:To investigate the lung function changes of hormone combined with immunosup-pressive in the treatment of dermatomyositis associated interstitial lung disease.Methods:40 patients with der-matomyositis in our hospital from January 2012 to January 2016 were selected,and retrospectively analyzed the clinical data of 40 patients,all patients were treated with hormone and immunosuppressive therapy,the changes of serum creatine kinase level and pulmonary function were observed before and after treatment.Results:After treatment, the levels of 40 cases of patients serum creatine kinase was improved, serum creatine kinase ( CK) values was significantly higher than those before, the difference was statistically significant ( P < 0.01);after treatment,patients with pulmonary function level was better than before treatment, the difference was statisti-cally significant (P<0.05).Conclusion:Dermatomyositis with interstitial lung disease with hormone and immu-nosuppressive therapy can effectively improve the pulmonary function, reduce the pain of patients, improve the therapeutic effect, the prognosis is good, it is worthy of clinical application.关键词
皮肌炎/肺间质病变/糖皮质激素/免疫抑制剂Key words
Dermatomyositis/Interstitial lung disease/Glucocorticoid/Immunosuppression引用本文复制引用
梁志强,姜凤云,赵蕾,王雪燕,常晓华,刘艳伶,王亚婷..皮肌炎相关的肺间质病变经激素联合免疫抑制剂治疗后肺功能变化[J].河北医学,2016,22(10):1600-1602,3.基金项目
河北省承德市科学技术研究与发展计划项目，(编号:20158001) （编号:20158001）
