河北医学2016，Vol.22Issue(10)：1626-1629,4.DOI:10.3969/j.issn.1006-6233.2016.10.017
磁共振动态增强扫描及弥散加权成像在乳腺癌诊断中的应用价值
The Application Value of Dynamic Enhanced MRI and Diffusion Weighted Imaging in the Diagnosis of Breast Cancer
摘要
Abstract
Objective:Objective: To investigate the application value of DCE-MRI and DWI in the diagnosis of breast cancer. Methods: A total of 78 cases of breast cancer patients were selected from January 2015 to October 2015 in our hospital and were identified as breast cancer. The diagnostic efficacy of DCE-MRI, DWI and the combination of the two methods were compared. Results: Fifty-three malignant lesions and 30 benign lesions were confirmed by histopathology. Sixty-four malignant lesions and 19 benign le-sions were detected by DCE-MRI, sensitivity 94.3%, specificity 53.3%, accuracy 79.5%, positive predictive value 78.1%, positive likelihood ratio 2.02, negative predictive value 84.2%, negative likelihood ratio 0.11, Youden index 0.476. Sixty-one malignant lesions and 22 benign lesions were detected by DWI, sensitivity 94. 3%, specificity 63. 3%, accuracy 83. 1%, positive predictive value 82. 0%, positive likelihood ratio 2. 59, negative predictive value 86.4%, negative likelihood ratio 0.09, Youden index 0.728. Fifty-four malignant le-sions and 29 benign lesions were detected combined DCE-MRI with DWI, sensitivity 96.2%, specificity 90. 0%, accuracy 94.0%, positive predictive value 94.4%, positive likelihood ratio 9.62, negative predictive val-ue 93.1%, negative likelihood ratio 0.04, Youden index 0.862. The application value of combined method was better than DCE-MRI and DWI. Conclusion:DCE-MRI combined with DWI can significantly improve the di-agnostic efficacy of breast cancer.关键词
动态增强扫描/弥散加权成像/乳腺癌Key words
Dynamic contrast enhanced scanning/Diffusion weighted imaging/Breast cancer引用本文复制引用
彭建波,李文武,范小涛,蒋康平,李传明..磁共振动态增强扫描及弥散加权成像在乳腺癌诊断中的应用价值[J].河北医学,2016,22(10):1626-1629,4.基金项目
国家自然科学基金，(编号:81000607) （编号:81000607）
