临床口腔医学杂志2016，Vol.32Issue(11)：643-645,646,4.DOI:10.3969/j.issn.1003-1634.2016.11.001
牙髓干细胞修复即刻种植周围骨缺损
Dental pulp stem cells repair the immediate implantation for peri-implant bone defects
摘要
Abstract
Objective:To establish an animal experimental model of the immediate implantation for peri-implant bone defects of the rabbit mandibular anterior teeth,and observe dental pulp stem cells to repair peri-implant bone defects.Meth-ods:The rabbits that the bilateral mandibular anterior teeth were extracted respectively were divided into 2 groups.Establis-hing bone defect of 2 mm ×3 mm area on the buccal side of tooth extraction socket,and the implant was implanted immedi-ately,that the control group was implanted with Bio-oss and the experimental group with Bio-oss and dental pulp stem cells ( DPSCs) .The implant-osseointegration condition could be evaluated by scanning electron microscope,HE staining.Results:Through scanning electron microscope,the formation of visible woven bone and trabecular bone on implant osseointegration interface of the experimental group could be observed,and the gap between implant and alveolar fossa basically disappeared and between the implant and gingival side decreased,the density of cancellous bone around the implant increased as well.HE staining showed that the cytoplasmic portion of alveolar bone around the implant was vacuole,and the osteoblasts and osteo-clasts were distributed on the trabecular bone,the trabecular bone was compact and regularly arranged.Conclusion:The es-tablishment of an animal experimental model of the immediate implantation for peri-implant bone defects of the rabbit man-dibular anterior teeth can provide an important reference for the relevant research about the immediate implantation direction.关键词
骨缺损/即刻种植/动物模型/修复Key words
Alveolour bone defect/Immediate-implant/Animal model/Repair分类
医药卫生引用本文复制引用
白慧子,木合塔尔·霍加,王腾,庄友梅..牙髓干细胞修复即刻种植周围骨缺损[J].临床口腔医学杂志,2016,32(11):643-645,646,4.基金项目
国家自然科学基金资助项目 （）
