器官移植2016，Vol.7Issue(6)：463-466,4.DOI:10.3969/j.issn.1674-7445.2016.06.010
肝移植术后腹腔出血原因分析及防治体会（附82例报告）
Analysis on cause,prevention and treatment of intra-abdominal hemorrhage after liver transplantation:a report of 82 cases
摘要
Abstract
Objective To investigate the cause,prevention and treatment of intra-abdominal hemorrhage after liver transplantation. Methods Clinical data of 82 patients undergoing liver transplantation were retrospectively analyzed. All participants were divided into the intra-abdominal hemorrhage (n =12)and control groups (n =70). Preoperative parameters including age,model for end-stage liver disease (MELD)score,prothrombin time (PT),prothrombin time international normalized ratio (PT-INR),fibrinogen (FIB),activated partial thromboplastin time (APTT),platelet (Plt) were statistically compared between two groups. Intraoperative hemorrhage volume,cold ischemia time of donor liver, anhepatic phase time and operation time were also compared between two groups. Postoperatively,the mortality rate was compared between two groups. Results Among 82 patients,1 2 (1 5%)presented with intra-abdominal hemorrhage and required twice surgical hemostasis. In the intra-abdominal hemorrhage group,4 cases (33%)died,and 8 (1 1%)died in the control group. No statistical significance was documented between two groups (P>0. 05 ). Age,MELD score,PT-INR, FIB,APTT and PLT did not significantly differ between two groups (all P>0. 05 ). Compared with patients in the control group,those in the intra-abdominal hemorrhage group yielded significantly more blood loss intraoperatively,longer operation time and longer cold ischemia time of donor liver (all P<0. 05 ). Anhepatic phase time did not significantly differ between two groups (P>0. 05 ). Conclusions After liver transplantation,intra-abdominal hemorrhage is associated with longer cold ischemia time of donor liver,more intraoperative blood loss and longer operation time. In order to decrease the incidence of postoperative intra-abdominal hemorrhage,coagulation function should be completely corrected prior to surgery and the surgical skills should also be enhanced.关键词
肝移植/腹腔出血/危险因素/冷缺血时间/出血量/手术时间Key words
Liver transplantation/Intra-abdominal hemorrhage/Risk factor/Cold ischemia time/Hemorrhage volume/Operation time分类
医药卫生引用本文复制引用
熊亮,黎利娟,安玉玲,魏绪霞,易慧敏..肝移植术后腹腔出血原因分析及防治体会（附82例报告）[J].器官移植,2016,7(6):463-466,4.基金项目
广东省科技计划项目 （）
