中国医疗设备2016，Vol.31Issue(11)：116-118,3.DOI:10.3969/j.issn.1674-1633.2016.11.033
乳腺癌根治术后适形和调强混合放疗计划与单纯调强放疗计划的剂量学比较
Dosimetry Comparison of IMRT with 3D-CRT and Simple IMRT for Breast Cancer after Radical Surgery
阮长利 1宋启斌 1胡钦勇 1付敬国 1张钧1
作者信息
- 1. 武汉大学人民医院 肿瘤中心，湖北武汉 430060
- 折叠
摘要
Abstract
Objective To compare the dosimetric distribution of Intensity Modulated Radiotherapy (IMRT) together with 3-Dimensional Conformal Radiation Therapy (3D-CRT) and simple IMRT for breast cancer after radical surgery in order to provide the basis for breast cancer radio therapy. Methods Altogether 20 breast cancer patients were collected. For each patient, the combination of IMRT and CRT as well as simple IMRT were designed with the prescription dose of 50 Gy /25 times so as to compare the dosimetric differences in Planning Target Volume (PTV) and Organs at Risk (OAR) of two plans. Results The PTV V95% of two plans were similar [(99.18±0.32)% and (99.43±0.47)% respectively] without statistically significant difference (P>0.05); V105% and V110% of IMRT together with 3D-CRT and simple IMRT were similar without statistically significant difference (P>0.05). Conformity Index (CI) and Homogeneity Index (HI) of combined plans were superior than those of simple IMRT, (P<0.05). In contrast with simple IMRT, ipsilateral lung V30, V20, V5 of combined plans were reduced by 2.68%, 3.25% and 27.38% respectively (P<0.05); cardiac V30, V40 and V50 were reduced by 3.18%, 2.27% and 1.52% respectively (P<0.05).Conclusion Compared with simple IMRT, combination of IMRT and 3D-CRT achieved better effects in dose distribution and CI and reduced the irradiation dose of lung, heart and other vital organs, which showed better application effects.关键词
乳腺癌/适形放射治疗/调强放射治疗/适形度指数/均匀性指数Key words
breast cancer/conformal radiotherapy/intensity modulated radiation therapy/conformal index/evenness index分类
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阮长利,宋启斌,胡钦勇,付敬国,张钧..乳腺癌根治术后适形和调强混合放疗计划与单纯调强放疗计划的剂量学比较[J].中国医疗设备,2016,31(11):116-118,3.
