中国病理生理杂志2016，Vol.32Issue(11)：2101-2105,2112,6.DOI:10.3969/j.issn.1000-4718.2016.11.032
先心病中microRNA对DNA甲基化的调控及其应用前景∗
Advances in modulation of microRNA and DNA methylation in congenital heart diseases
摘要
Abstract
Aberrations in microRNA (miRNA) expression and DNA methylation are causal factors for con-genital heart diseases ( CHD) , which belongs to epigenetic mechanisms. Complex modulation of miRNA on DNA methyla-tion is a critical regulator of gene expression, leading to disease development. The aim of this review is to provide recent progress in the regulation of miRNA and DNA methylation in CHD.关键词
先天性心脏病/微小RNA/DNA甲基化Key words
Congenital heart diseases/MicroRNA/DNA methylation分类
医药卫生引用本文复制引用
杨倩,桂永浩,李强..先心病中microRNA对DNA甲基化的调控及其应用前景∗[J].中国病理生理杂志,2016,32(11):2101-2105,2112,6.基金项目
国家自然科学基金资助项目(No.81470442) （No.81470442）
