中国临床医学2016，Vol.23Issue(5)：662-666,5.DOI:10.12025/j.issn.1008-6358.2016.20160175
STAT3蛋白调节Th 17细胞的分化及其与自身免疫相关性血液疾病的关系
STAT3 in regulating Th17 differentiation and its relationship with autoimmune hematological diseases
摘要
Abstract
Signal transducers and activators of transcription (STAT ) are mainly involved in cellular signal transduction.Among them,STAT3 is particularly important in promoting the differentiation of Th17 cells.Aberrant activation of STAT3 signaling pathway has been confirmed to be related to a number of autoimmune hematological diseases, such as immune thrombocytopenia (ITP),aplastic anemia (AA),and autoimmune hemolytic anemia (AIHA).This paper has reviewed the relationship between STAT3,Th17 cell differentiation and autoimmune hematological diseases.关键词
STAT3/Th1 7细胞/自身免疫相关性血液疾病Key words
STAT3/Th1 7/autoimmune hematological diseases分类
医药卫生引用本文复制引用
柯杨,程韵枫..STAT3蛋白调节Th 17细胞的分化及其与自身免疫相关性血液疾病的关系[J].中国临床医学,2016,23(5):662-666,5.基金项目
国家自然科学基金（81170473，81470282）．Supported by National Natural Science Foundation of China（81170473，81470282）． （）
