摘要
Abstract
Objective To discuss the treatment effect of kangfuxin solution on ammoniac halitosis and burning pain in oral mucosa of hemodialysis patients with end-stage renal disease ( ESRD) .Methods Among the 110 ESRD patients who received hemodialysis in the Affiliated Hospital of Xuzhou Medical University, 63 patients with ammoniac halitosis ( OS≥2 ) were selected from January to October of 2013.The patients were divided into control group ( n=31 ) and experiment group ( n=32) by random number table method.Patients in both of the two groups received oral hygiene instruction and training of using mouthwash, patients in control group used compound chlorhexidine gargle, while patients in experiment group chose kangfuxin solution, and the treatment time lasted for 2 weeks.The ammoniac halitosis indicators 〔including OS, oral ammonia value (OAV), pH value of saliva〕, other oral examinations conditions 〔including thickness of the tongue (Tt), area of the tongue (Ta), staining index (SI)〕 of patients in two groups, and pain index 〔including pain rating scale (PRI), visual analogue scale (VAS), present pain index (PPI)〕 of those patients with burning pain in the oral mucosa (PPI≥1) were detected and compared before and after treatment in both groups.Results There was no significant difference in OS, OAV and pH of saliva between patients in two groups before and after treatment (P>0.05) .The number of patients with PPI≥1 were 41 in total, the difference before and after treatment of PRI and VAS of patients with PPI≥1 in experiment group were significantly higher thanthat in control group (P <0.05) .There was no significant difference in the PPI difference before and after treatment of patientsin two groups (P >0.05) .The differences before and after treatment of Ta, Tt and SI were not significantly different (P >0.05) .Conclusion Kangfuxin solution can alleviate burning pain in oral mucosal of ESRD hemodialysis patients with ESRD,and its effect is better than chlorhexidine solution; but it has no advantage in the treatment of ammonia halitosis compared withchlorhexidine solution.关键词
肾功能衰竭, 慢性/肾透析/口臭/黏膜烧灼性疼痛/康复新液/治疗结果Key words
Kidney failure, chronic/Renal dialysis/Halitosis/Oral mucosal burning pain/Kangfuxin solution/Treatment outcome分类
医药卫生
