中国全科医学2016，Vol.19Issue(32)：4014-4018,5.DOI:10.3969/j.issn.1007-9572.2016.32.024
间充质干细胞应用于类风湿关节炎组织修复的研究进展
Research Prognosis of Application of Mesenchymal Stem Cells in the Tissue Repair of Rheumatoid Arthritis
张香梅 1田中良哉 2单保恩1
作者信息
- 1. 050011河北省石家庄市，河北医科大学第四医院科研中心，河北省肿瘤基因诊断 预防和治疗重点实验室
- 2. 日本国北九州市日本产业医科大学第一内科学
- 折叠
摘要
Abstract
Rheumatoid arthritis ( RA) is an autoimmune disease characterized by synovitis and articular injury due to synovitis.The current available treatments for RA mainly control synovitis, but have little effects on articular destruction repair.Mesenchymal stem cells ( MSC) have effects on immunological regulation, and have the ability of multiple differentiation potential, so MSC have the potential to control synovitis and repair articular destruction.Until now, some researchers have reported the application of MSC in the treatment of RA patients or RA animal models, while these studies lead to different conclusions, and few studies focused on the effects of articular destruction.The studies on application of MSC in the tissue repair of RA are summarized in this article, which may provide the reference for clinical treatment.关键词
关节炎, 类风湿/间质干细胞/炎症/关节软骨修复/综述Key words
Arthritis, rheumatoid/Mesenchymal stem cells/Inflammation/Articular cartilage repair/Review分类
医药卫生引用本文复制引用
张香梅,田中良哉,单保恩..间充质干细胞应用于类风湿关节炎组织修复的研究进展[J].中国全科医学,2016,19(32):4014-4018,5.
