中国全科医学2016，Vol.19Issue(32)：4019-4022,4.DOI:10.3969/j.issn.1007-9572.2016.32.025
Twist基因在卵巢癌中的研究进展
Research Progress of Twist Gene in Ovarian Cancer
摘要
Abstract
Ovarian cancer is a gynecologic malignant tumor with morbidity in the third place after endometrial cancer and cervical cancer, its fatality rate ranks first in gynecologic malignant tumors.Twist in the transcription factor of basic helix-loop-helix ( bHLH) family is highly expressed in ovarian cancer tissues, and its abnormal expression plays an important role in the process of occurrence, development and deterioration of the ovary.After silence processing of Twist gene, proliferation and migration of ovarian carcinoma cells will be obviously affected.By combining recent research results at home and abroad, the paper outlines the latest mechanism of Twist gene in the occurrence and development of ovarian cancer.关键词
卵巢肿瘤/Twist基因/细胞增殖/综述Key words
Ovarian neoplasms/Twist gene/Cell proliferation/Review分类
医药卫生引用本文复制引用
洪莉,杨将,邢辉..Twist基因在卵巢癌中的研究进展[J].中国全科医学,2016,19(32):4019-4022,4.基金项目
湖北省卫计委面上项目(JX6B105）；湖北省卫计委重点项目(WJ2015MA024） （）
