中国药房2016，Vol.27Issue(32)：4486-4489,4.DOI:10.6039/j.issn.1001-0408.2016.32.07
我院急性胰腺炎患者抗菌药物使用分析
Analysis of the Utilization of Antimicrobial Agents in Patients with Acute Pancreatitis in Our Hospital
摘要
Abstract
OBJECTIVE:To evaluate the situation and rationality of the implementation of antimicrobial therapy for patients with acute pancreatitis (AP)in our hospital. METHODS:132 AP patients admitted into our hospital during Aug. 2013-Dec. 2015 were selected and analyzed statistically in respects of the types of antimicrobial agents,drug combination,usage and dosage,etc. The rationality of antimicrobial agents use was also analyzed. RESULTS:Among 132 AP patients,there were 103 men and 29 women;mean age of them was (43.75 ± 1.26) years;mild acute pancreatitis (MAP,117 cases) accounted for 88.64%,and se-vere acute pancreatitis(SAP,15 cases)accounted for 11.36%;the top 3 causes of AP were obstruction factors(32.31%),hyper-lipidermia(27.21%)and alcohol(18.03%),respectively. Main symptoms were abdominal pain,abdominal distension and vomit-ing;among 132 AP patients,101 cases were cured and 31 cases were recovered. The antimicrobial agents were used in 107 MAP cases and 13 SAP cases,and the total utilization ratio was 90.91%(of which,90.15% belonged to therapeutic drug use). A total of 5 species were used,the combination proportion of which was 77.28%,among which two-drug combination was the most (69.70%),mainly including“sulbactam sodium and cefoperazone+tinidazole”(45.65%)and“levofloxacin+tinidazole”(27.17%). After treatment,patient’s serum amylase level MEUT and WBC recovered to normal range. CONCLUSIONS:The utilization of an-timicrobial agents in our hospital is basic reasonable for AP patients,meat the requirements of the releveant guidelines. The rational-ity of prophylactic use of agents remain to be discussed.关键词
急性胰腺炎/抗菌药物/合理性评价Key words
Acute pancreatitis/Antimicrobial agents/Rationality evaluation分类
医药卫生引用本文复制引用
张蔚,黄丽,龙丽辉..我院急性胰腺炎患者抗菌药物使用分析[J].中国药房,2016,27(32):4486-4489,4.基金项目
陕西省大学生创新训练项目 （）
