摘要
Abstract
OBJECTIVE:To observe the effects and safety of Qijiao shengbai capsule on cardiac function,fenal tunction,pe-ripheral routine blood test and celluar immunity indexes of patients with myocardial infarction complicated with hypertension. METHODS:58 patients with myocardial infarction complicated with hypertension in our hospital were selected and divided into control group and the observation group,with 29 cases in each group according to the even and odd number of hospitalization or-der. Control group was given symptomatic treatment as bringing down high blood pressure,regulating blood lipid and preventing myocardial infarction. On this basis,observation group was additionally treated with Qijiao shengbai capsule 2.0 g,po,tid. Treat-ment course of 2 groups lasted for 6 months. Cardiac function,renal function,peripheral routine blood test,Tcell subset and the oc-currence of ADR were observed in 2 groups before and after treatment. RESULTS:Before treatment,there were no statistical sig-nificance in above indexes between 2 groups(P>0.05). After treatment,LVSd,LVDd,IVSDT and LVPWT of 2 groups were all decreased significantly,with statistical significance (P<0.05);there was no statistical significance between 2 groups (P>0.05). MAU and UA of observation group and MAU of control group were decreased significantly after treatment;eGFR of observation group was increased significantly,with statistical significance(P<0.05). The improvement of above indexes in observation group were significantly better than in control group,with statistical significance(P<0.05). The change of peripheral routine blood index-es and T lymphocyte subset in obserration group were greater than in control group,with statistical signifrcance(P<0.05). No ob-vious ADR was found in observation group. CONCLUSIONS:Qijiao shengbai capsule do not influence cardiac function of myocar-dial infarction patients with hypertension,can protect renal function and strengthen body immunity function with good safety.关键词
心肌梗死伴高血压/芪胶升白胶囊/心脏功能/肾功能/T细胞亚群Key words
Myocardial infarction complicated with hypertension/Qijiao shengbai capsule/Cardiac funetion/Renal function/T cell subset分类
医药卫生
