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妥洛特罗对咳嗽变异性哮喘患儿EOS和PEF的影响研究

吴文红 吴海谊 谢文锐

中国医药科学2016,Vol.6Issue(17):59-61,3.
中国医药科学2016,Vol.6Issue(17):59-61,3.

妥洛特罗对咳嗽变异性哮喘患儿EOS和PEF的影响研究

Influence study on EOS and PEF in children with cough variant asthma by Toy Lotero

吴文红 1吴海谊 1谢文锐1

作者信息

  • 1. 广东省东莞市人民医院,广东东莞 523059
  • 折叠

摘要

Abstract

Objective To study the change situation of EOS on and PEF in children with cough variant asthma by Toy Lo Tero. Methods 89 cases of children with cough variant asthma cured in outpatient treatment of cough variant asthma of our hospital from January 2014 to January 2016 were selected. According to the different treatment methods, they were divided into observation group(43 cases)and control group(46 cases). Patients in control group were treated with antihistamine drugs combined with selective leukotriene receptor antagonist treatment, and patients in observation group were treated with tulobuterol patch(0.5mg/ paste, Nitto denko) every night 1 stick, stick in the chest, back and upper arm can be, 24 h replacement QD for 14 d. The curative effects of the two groups after treatment and the changes of EOS, and PEF, PEFR after treatment in two groups were compared. Results The total effective rate of observation group was 95%, the total effective rate of control group was 72%, the clinical curative effect of observation group was significantly better than that of control group, and the difference between the two groups was significant(P < 0.05). After treatment, the EOS, PEFR of the two groups were significantly decreased, and PEF was significantly increased. The changes of EOS, PEFR and PEF in observation group were more significant than those of control group(P < 0.05). Conclusion The proper treatment of cough variant asthma can improve the clinical efficacy, improve pulmonary function, and exert anti-inflammatory effects by reducing EOS.

关键词

咳嗽变异性哮喘/妥洛特罗/EOS/PEF

Key words

Cough variant asthma/Toy Lotero/EOS/PEF

分类

医药卫生

引用本文复制引用

吴文红,吴海谊,谢文锐..妥洛特罗对咳嗽变异性哮喘患儿EOS和PEF的影响研究[J].中国医药科学,2016,6(17):59-61,3.

基金项目

广东省东莞市医疗卫生科技计划项目(2014105101201)。 ()

中国医药科学

2095-0616

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