中国医药科学2016，Vol.6Issue(17)：195-197,3.
IGF-1、TGF-β1在早产儿视网膜病中的表达及临床意义
Expression of IGF-1 and TGF-β1 in retinopathy of prematurity and its clinical significance
摘要
Abstract
Objective To observe the expression of IGF-1 and TGF-β1 in retinopathy of prematurity and its clinical significance. Methods Data were from the data of premature infant in our hospital from November 2011 to October 2013. 30 cases occurred ROP were selected as ROP group, 30 cases un-occurred ROP were selected as premature control group, and 30 cases of healthy full-term newborn infants over the same period were selected as full-term control group. The contents of IGF-1 and TGF-β1 in each group were compared. Results Serum contents of IGF-1 and TGF-β1 at 1 week after birth, 32 weeks of gestational age, 34 weeks of gestational age and 36 weeks of gestational age of ROP group were respectively lower than those of un-occurred ROP and full-term control group (P < 0.05). But there was no statistical significance in the contents of IGF-1 and TGF-β1 at 40 of gestational age between ROP group, un-occurred ROP group and full-term control group (P > 0.05). Conclusion Both IGF-1 and TGF-β1 are involved in the occurrence and development of the occurrence and development of retinopathy of premature infants. By dynamic monitoring the change of IGF-1 and TGF-β1, it is benefit to provide reference for the diagnosis and treatment of retinopathy of premature infants.关键词
外周血胰岛素样生长因子/转化生长因子/早产儿视网膜病/新生血管Key words
Peripheral blood insulin like growth factor/Transforming growth factor/Retinopathy of retinopathy/New blood vessel分类
医药卫生引用本文复制引用
陈健萍,袁海超,赵云开,卢燕玲..IGF-1、TGF-β1在早产儿视网膜病中的表达及临床意义[J].中国医药科学,2016,6(17):195-197,3.基金项目
广东省东莞市科技计划医疗卫生类科研项目（201110515001099）。 （）
