中国中医药信息杂志2016，Vol.23Issue(12)：30-33,4.DOI:10.3969/j.issn.1005-5304.2016.12.008
疏风止嗽方治疗咳嗽变异性哮喘临床研究
Clinical Study on Cough Variant Asthma Treated with Shufeng Zhisou Formula
摘要
Abstract
Objective To evaluate the clinical efficacy of Shufeng Zhisou Formula in treating cough variant asthma (CVA). Methods Totally 120 CVA patients were randomly divided into TCM group, WM group and integrated TCM and WM group, with 40 cases in each group. TCM group was treated with Shufeng Zhisou Formula;WM group was treated with Seretide; integrated TCM and WM group was treated with Shufeng Zhisou Formula and Seretide. One course of treatment was twenty-eight days for each guoup. TCM syndrome scores, self testing cough scores, EOS numbers, IgE concentration and lung function before and after treatment in the three groups were compared. Results The markedly effective rate was 45.00% in the TCM group, 20.00% in the WM group and 85.00% in the integrated TCM and WM group. The total effective rate of TCM group was 97.50%in the TCM group, 77.50%in the WM group and 95.00%in the integrated TCM and WM group, with statistical significance (P<0.05). After treatment, the total TCM syndrome scores in the three groups were significantly improved (P<0.01), and those of TCM group and integrated TCM and WM group were superior to those of WM group (P<0.05). EOS numbers of integrated TCM and WM group and IgE concentration of the three groups significantly decreased (P<0.05), without statistical significance (P>0.05). The lung function of the three groups significantly improved (P<0.05), without statistical significance (P>0.05). The difference on bronchial provocation test negative rate among the three groups was with no statistical significance (P>0.05). Conclusion Shufeng Zhisou Formula has good clinical efficacy in treating CVA. The action mechanism may be related to anti-allergic inflammation and reducing airway responsiveness.关键词
疏风止嗽方/咳嗽变异性哮喘/临床研究Key words
Shufeng Zhisou Formula/cough variant asthma/clinical study分类
医药卫生引用本文复制引用
卢世秀,庞磊,李步满,尹李虎,向平超,张二明,王雪京,屈毓敏,郑玉琴,刘培红..疏风止嗽方治疗咳嗽变异性哮喘临床研究[J].中国中医药信息杂志,2016,23(12):30-33,4.基金项目
北京市中医管理局科技提升专项基金 （）
