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不同产地鱼腥草中槲皮苷含量测定

印晓红 金汉台 谭林威 何林旺 王建方 闵会 胡江宁

中国中医药信息杂志2016,Vol.23Issue(12):78-80,3.
中国中医药信息杂志2016,Vol.23Issue(12):78-80,3.DOI:10.3969/j.issn.1005-5304.2016.12.019

不同产地鱼腥草中槲皮苷含量测定

Determination of Quercitrin in Houttuyniae Herba from Different Producing Areas

印晓红 1金汉台 2谭林威 3何林旺 1王建方 2闵会 3胡江宁1

作者信息

  • 1. 浙江康恩贝制药股份有限公司药品研发中心,浙江 杭州 310052
  • 2. 浙江省中药制药技术重点实验室,浙江 杭州 310052
  • 3. 浙江康恩贝中药有限公司,浙江 丽水 323400
  • 折叠

摘要

Abstract

Objective To establish a method to determine the content of quercitrin in Houttuyniae Herba; To compare the differences in the content of quercitrin in Houttuyniae Herba from different producing areas. Methods HPLC was used with octadecylsilane-bonded silica gel as the stationary phase and a mixture of acetonitrile and 0.5%HAc (19:81) as the mobile phase. The detection wavelength was 256nm.vThe flow rate was 1.0 mL/min. Results It was shown that quercitrinwas in a good linear relationship in the range of 0.064 56–3.228 µg. The average recovery of quercitrin was 97.68%, RSD=1.3%(n=6). Houttuyniae Herba from Sichuan Province contains the highest content of quercitrin. Conclusion This method is simple and rapid, with stability, reliability and strong specificity. The contents of quercitrin in Houttuyniae Herba from different producing areas were quite different.

关键词

高效液相色谱法/鱼腥草/槲皮苷/含量测定/不同产地

Key words

HPLC/Houttuyniae Herba/quercitrin/content determination/different producing areas

分类

医药卫生

引用本文复制引用

印晓红,金汉台,谭林威,何林旺,王建方,闵会,胡江宁..不同产地鱼腥草中槲皮苷含量测定[J].中国中医药信息杂志,2016,23(12):78-80,3.

基金项目

浙江省科技计划项目 ()

中国中医药信息杂志

OACSCDCSTPCD

1005-5304

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