中国中医药信息杂志2016，Vol.23Issue(12)：81-85,5.DOI:10.3969/j.issn.1005-5304.2016.12.020
星点设计-效应面法优选制巴戟天炮制工艺
Optimization of Liqorice-Processing Technology of Morinda officinalis How by Central ;Composite Design-Reponse Surface Methodology
摘要
Abstract
Objective To optimize the licorice-processing technology of Morinda officinalis How. Methods Morinda officinalis How was selected as raw materials. Single-factor experiment was used to select licorice-juice amount, boiling time and moistening time as independent variables, the comprehensive scores of contents of rubiadin-1-methylether, nystose, monotropein, liquiritin, glycyrrhizinate as the dependent variables. The central composite design and response surface methodology was employed to optimize processing technology of Morinda officinalis How. Results The optimized processing parameters consisted of 1.5 times the amount of licorice juice, moistening 4 h, boiling 25 min. The deviation between real measured value and predicted value of OD was 1.39%. Conclusion The central composite design and response surface methodology for optimizing licorice-processing technology of Morinda officinalis How is stable, feasible and highly predictable, which can provide references for standardizing production of Morinda officinalis How.关键词
制巴戟天/星点设计-效应面法/炮制工艺Key words
Morinda officinalis How/central composite design and response surface methodology/processing technology分类
医药卫生引用本文复制引用
史辑,黄玉秋,耿彤彤,范亚楠,贾天柱..星点设计-效应面法优选制巴戟天炮制工艺[J].中国中医药信息杂志,2016,23(12):81-85,5.基金项目
国家自然科学基金（81473350）；国家自然科学基金青年基金 （）
