中国卒中杂志2016，Vol.11Issue(11)：912-917,6.DOI:10.3969/j.issn.1673-5765.2016.11.003
阻塞性睡眠呼吸暂停与觉醒型卒中的关系分析
Correlation Analysis of Obstructive Sleep Apnea and Wake-up Stroke
摘要
Abstract
Objective To explore the relationship between obstructive sleep apnea (OSA) and wake-up stroke (WUS). <br> Methods The clinical data of patients with ischemic stroke accompanied with OSA were analyzed retrospectively. The patients received sleep monitoring examination at night and were divided into WUS group and non wake-up stroke (non-WUS) group. The differences of the clinical data, National Institutes of Health Stroke Scale (NIHSS) score, etiology and the slee respiratory parameters were compared between the two groups. <br> Results A total of 96 patients were included, among whom, there was 74 cases in non-WUS group and 22 cases in WUS group. The body mass index (BMI) (P=0.030), apnea-hypopnea index (AHI) (P=0.001), and oxygen desaturation index (ODI) (P=0.001) in WUS group were higher than those in non-WUS group. The mean blood pulse oxyhemoglobin saturation (P=0.002) in WUS group was lower than which in non-WUS group. Binary logistic regression analysis indicated that the independent risk factor for WUS was AHI (odds ratio [OR] 1.162, 95% conifdence interval [CI] 1.007~1.341). <br> Conclusion BMI, AHI, ODI and mean blood pulse oxyhemoglobin saturation are associated with WUS. AHI is an independent risk factor for WUS.关键词
阻塞性睡眠呼吸暂停/觉醒型卒中/呼吸暂停低通气指数Key words
Obstructive sleep apnea/Wake-up stroke/Apnea-hypopnea index引用本文复制引用
刘伟,周正宏,史冬梅,刘磊,谢子珍,翟安琪,于逢春,樊东升..阻塞性睡眠呼吸暂停与觉醒型卒中的关系分析[J].中国卒中杂志,2016,11(11):912-917,6.基金项目
北京大学985工程（临床医院合作专项）建设项目（题目缺血性脑卒中现代化预防理论体系及全方位预警机制）北京市海淀医院（北京大学第三医院海淀院区）重点课题 （）
