中国卒中杂志2016，Vol.11Issue(11)：918-922,5.DOI:10.3969/j.issn.1673-5765.2016.11.004
日间嗜睡与急性缺血性卒中短期预后的关系
Correlation of Daytime Sleepiness and Acute Ischemic Stroke
摘要
Abstract
Objective By analyzing the relationship between daytime sleepiness and neurological function prognosis in patients with acute stroke, to explore the relationship between daytime sleepiness and acute ischemic stroke. <br> Methods Patients with acute ischemic stroke within 48 hours were consecutively enrolled from Beijing Haidian Hospital during June 2015 to September, 2015. And data were collected including demographics, chronic disease history, National Institutes of Health Stroke Scale (NIHSS) on admission and the 14th day, and Epworth Sleepiness Scale (ESS) on admission. ESS 1 month before admission, which is the premorbid ESS, were retrospectively evaluated. The correlation between premorbid ESS with demographics, chronic disease history, NIHSS on admission and the 14th day, delta NIHSS (the result of NIHSS on admission minus NIHSS of the 14th day) and ESS on admission were analyzed. According to premorbid ESS, patients were divided into sleepiness group and non-sleepiness group, compared NIHSS on admission and the 14th day, delta NIHSS and ESS on admission between two groups. <br> Results One hundred and six patients were consecutively enrolled. The results showed that①Premorbid ESS had positive correlation with admission NIHSS, the 14th day NIHSS and admission ESS. Pearson correlation coefifcient were 0.199, 0.276 and 0.407, andP values were 0.041, 0.004 and <0.001. Premorbid ESS had negative correlation with delta NIHSS. Pearson correlation coefifcient was-0.189 andP value was 0.042.② In daytime sleepiness group, admission NIHSS, the 14th NIHSS and admission ESS were signiifcantly higher than in non-daytime sleepiness group. P values were 0.033, 0.043 and <0.001 respectively. In daytime sleepiness group, delta NIHSS was signiifcantly lower than in non-daytime sleepiness group.P value was 0.046. <br> Conclusion Premorbid daytime sleepiness patients will be more severely on admission and in 14th day, meanwhile their prognosis in the acute phase is worse. The degree of daytime sleepiness will aggravate when ischemic stroke happens.关键词
日间嗜睡/缺血性卒中/急性期Key words
Daytime sleepiness/Ischemic stroke/Acute phase引用本文复制引用
谢子珍,李常红,孟晓梅,于逢春..日间嗜睡与急性缺血性卒中短期预后的关系[J].中国卒中杂志,2016,11(11):918-922,5.基金项目
北京市海淀医院（北京大学第三医院海淀院区）重点课题 （）
