动物营养学报2016，Vol.28Issue(11)：3626-3633,8.DOI:10.3969/j.issn.1006-267x.2016.11.032
纳米氧化锌对断奶仔猪生长性能、血清免疫和生化指标的影响
Effects of Zinc Oxide Nanoparticles on Growth Performance, Serum Immune and Biochemical Indices of Weaned Piglets
王彬 1刘路杰 1祝佳 1邹君彪 2冷董碧 2王敏奇1
作者信息
- 1. 浙江大学动物科学学院，杭州 310058
- 2. 江西兴鼎科技有限公司，南昌 330115
- 折叠
摘要
Abstract
This study was conducted to investigate the effects of different doses of dietary zinc oxide nanoparti⁃cles on growth performance, serum immune and biochemical indices of weaned piglets. A total of 150 28⁃day⁃old weaned piglets (Duroc×Landrace×Yorkshire) with an initial average body weight of (9.37±0.48) kg were randomly assigned into 5 groups with 3 replicates per group and 10 piglets per replicate. The piglets in the con⁃trol group were fed a basal diet, in high zinc oxide group were fed the basal diet supplemented with 3 000 mg/kg common zinc oxide, and in three trial groups ( group 1, 2 and 3) were fed the basal diet supple⁃mented with 150, 300 and 450 mg/kg zinc oxide nanoparticles, respectively. The experiment lasted for 21 days. The results showed as follows:1) compared with the control group, dietary supplementation of zinc ox⁃ide nanoparticles significantly increased the average daily feed intake and average daily gain ( P<0.05) , signif⁃icantly decreased the ratio of feed to gain and diarrhea rate ( P<0.05) of pigs, and the optimal supplemental levels of zinc oxide nanoparticles were 300 and 450 mg/kg which had the similar effects with common zinc ox⁃ide. 2) Compared with the control group, dietary zinc oxide nanoparticles and common zinc oxide significantly increased the contents of serum immunoglobulin A, interleukin⁃6 and tumor necrosis factor⁃α ( P<0.05) , and significantly reduced serum urea nitrogen content ( P<0.05) . These results suggest that dietary supplementation of 300 or 450 mg/kg zinc oxide nanoparticles has beneficial effects on immunity of weaned piglets, which also can increase their growth performance and decrease diarrhea rate. Accordingly, the new zinc oxide nanoparti⁃cles have a potential to substitute common zinc oxide.关键词
纳米氧化锌/断奶仔猪/生长性能/细胞因子/免疫指标/血清生化指标Key words
zinc oxide nanoparticles/weaned piglets/growth performance/cytokines/immune indices/ser-um biochemical indices分类
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王彬,刘路杰,祝佳,邹君彪,冷董碧,王敏奇..纳米氧化锌对断奶仔猪生长性能、血清免疫和生化指标的影响[J].动物营养学报,2016,28(11):3626-3633,8.
