中国妇幼健康研究2016,Vol.27Issue(10):1231-1233,3.DOI:10.3969/j.issn.1673-5293.2016.10.021
联合振幅整合脑电图及弥散加权成像在诊断新生儿脑损伤的价值
Value of amplitude integrated electroencephalogram combining diffusion weighted imaging in diagnosing neonatal brain injury
孟远翠 1范金超 1郑玲芳1
作者信息
- 1. 西安医学院第二附属医院新生儿科,陕西西安710038
- 折叠
摘要
Abstract
Objective To investigate the early diagnostic value of combining amplitude integrated electroencephalogram ( aEEG ) with diffusion weighted imaging (DWI) on neonatal brain injury.Methods Retrospective analysis was conducted among 48 cases of neonatal brain injury hospitalized in the Second Affiliated Hospital of Xi''an Medical College during May 2013 to May 2015.Seven days after birth aEEG and DWI were performed to observe the sensitivity and specificity.Three months after birth the cases were reexamined to understand the recovery of neonatal brain injury.Neonatal behavior neurological assessment (NBNA) was done 7 days after birth and Bayley score was assessed at 3 month after birth to explore the correlation between different changes of imaging and neonatal recent nervous system prognosis. Results Both aEEG and DWI could detect neonatal brain injury sensitively.The sensitivity of aEEG and DWI was 60.41%and 54.16%, respectively, and the joint diagnostic sensitivity was 79.16%.The positive rates of aEEG and DWI reduced obviously at 3 month compared to those at day 7.The joint diagnostic sensitivity was 79.16%and 56.25%at day 7 and 3 month, respectively, which was higher than that of single aEEG or DWI.Abnormality of aEEG was closely related with NBNA score and Bayley score.Conclusion Combining aEEG and DWI makes great help to early diagnosis and early prevention of neonatal brain injury.Continuous monitoring has an important guidance for clinical diagnosis and provides evidence for early diagnosis and prevention of neonatal brain injury.关键词
新生儿/脑损伤/振幅整合脑电图/弥散加权成像Key words
neonates/brain injury/amplitude integrated electroencephalogram ( aEEG)/diffusion weighted imaging ( DWI)分类
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孟远翠,范金超,郑玲芳..联合振幅整合脑电图及弥散加权成像在诊断新生儿脑损伤的价值[J].中国妇幼健康研究,2016,27(10):1231-1233,3.