摘要
Abstract
Objective:To observed the changes in macular choroidal volume (MCV) before and atfer laser treatment for diabetic retinopathy (DR) with enhanced depth imaging spectral-domain optical coherence tomography (OCT-EDI). Methods:Clinical data of 30 patients (51 eyes) diagnosed severe non-proliferative (NPDR) and early proliferative diabetic retinopathy (PDR) with macular edema by examinations of optical coherence tomography (OCT) and fundus fluorescein angiography (FFA). All eyes were treated with grid laser photocoagulation and underwent panretinal photocoagulation (PRP) 1 week atfer treatment. hTe eyes were scanned by OCT-enhanced-depth imaging (EDI) at the time of before treatment of laser, 1 week, 1 month and 3 months atfer macular grid photocoagulation and PRP. Data of MCV were measured. Results:MCV were (6.38±0.69) mm3 before treatment of laser, MCV were (7.79±0.70) mm3 atfer macular grid photocoagulation, (1.56±0.32) mm3 larger than before treatment and with significant difference (t=3.265, P<0.05). MCV were (7.01±0.71) mm3 after PRP 1 month later, (1.21±0.31) mm3 larger than before treatment and with signiifcant difference (t=3.237, P<0.05), MCV were (6.11±0.57) mm3 atfer PRP 3 months later, (0.87±0.22) mm3 smaller than before treatment and with signiifcant difference (t=3.305, P<0.05). Conclusion:MCV increased significantly after macular grid photocoagulation 1 week later and PRP 1 month later, MCV decreased after PRP 3 months later. OCT-EDI can noninvasively and intuitively observe the choroidal changes of macular.关键词
糖尿病视网膜病变/激光光凝术/脉络膜体积/光学相干断层扫描/增强深度成像技术Key words
diabetic retinopathy/laser coagulation/choroidal volume/optical coherence tomography/enhanced depth imaging
