摘要
Abstract
Objective Research with pulmonary infection control window (PIC)combined with modified Glasgow Coma Scale (GCS)score in acute exacerbation of chronic obstructive pulmonary disease(AECOPD)were treated with sequential mechanical ven-tilation with noninvasive a switch in the treatment efficacy and evaluation and analysis.Methods Selected in our hospital in Jan-uary 2012 to June 2015 treated 182 cases of chronic obstructive pulmonary disease acute exacerbation(AECOPD) patients with in-vasive noninvasive sequential mechanical ventilation in the treatment,were randomly divided into two research group and the control group two groups,the team switch timing for a pulmonary infection control window (PIC) modified Glasgow coma scale (GCS) is a group of 15 points and stabilize 2 h,the control switch timing for pulmonary infection control window (PIC).The incidence rate of VAP,the retention time of endotracheal intubation,total time of invasive ventilation,total mechanical ventilation time,ICU time,re intubation rate and mortality rate were compared between the two groups.Results Research group ICU length of time and the total duration of mechanical ventilation is smaller than control group,and significant difference (P<0.05),reintubation rate was far less than the control group,also have significant differences (P<0.05),but two groups of patients with VAP occurred rate and mortality difference was not significant (P>0.05).Conclusion Pulmonary infection control window (PIC) window combined with modified Glasgow Coma Scale(GCS) score group reached 15 points and stable 2h in COPD acute exacerbation(AECOPD)with the switching of sequential ventilation can reduce reintubation rate and total duration of mechanical ventilation and ICU stay and have important clinical significance,it is worth of clinical application.关键词
慢性阻塞性肺疾病急性加重期/肺部感染控制窗/改良格拉斯哥昏迷指数(GCS)评分/序贯机械通气/切换时机Key words
AECOPD/GCS/Pulmonary infection control window/Sequential noninvasive mechanical ventilation/Switching point分类
医药卫生