现代妇产科进展2016，Vol.25Issue(11)：842-845,4.DOI:10.13283/j.cnki.xdfckjz.2016.11.009
基础雄激素及卵泡液雄激素水平与卵巢反应性及妊娠结局关系的探讨
Association of testosterone in serum and follicular fluid with ovarian response and preg-nancy outcomes
摘要
Abstract
Objective:To detect relationship between the basal serum/follicular fluid testosterone( T) level and ovarian response and pregnancy outcomes. Methods:A total of 130 infertile women undergoing IVF/ICSI were included. Patients were divided into 2 groups:Group 1:patients with diminished ovarian reserve;Group 2:patients with normal ovarian reserve. The basal serum/follicular fluid T levels were detected by ELISA. Results:There were significant differences in the basal serum T level between poor ovarian response( POR) patients and nor-mal ovarian response(NOR) patients in Group 1,whereas not in Group 2. There were no signifi-cant differences in follicular fluid T level between POR and NOR patients in both groups. Basal serum and follicular fluid T levels were not different between pregnant and non-pregnant pa-tients in both groups. Conclusion:In women with diminished ovarian reserve, basal serum T level could predict ovarian response,but could not predict pregnancy outcome;follicular fluid T level was irrelevant to ovarian response and pregnancy outcome. In women with normal ovarian reserve,basal serum and follicular fluid T levels were not associated with ovarian response andpregnancy outcome.关键词
雄激素/卵巢储备/卵巢反应性/妊娠结局Key words
Testosterone/Ovarian reserve/Ovarian response/Pregnancy outcome分类
医药卫生引用本文复制引用
张阳阳,郐艳荣,王晟,薛晴,尚,徐阳..基础雄激素及卵泡液雄激素水平与卵巢反应性及妊娠结局关系的探讨[J].现代妇产科进展,2016,25(11):842-845,4.基金项目
北京大学第一医院科研基金资助项目(No:2015QN029) （No:2015QN029）
