诊断学理论与实践2016,Vol.15Issue(5):464-467,4.DOI:10.16150/j.1671-2870.2016.05.006
不同食管静脉曲张内镜治疗方法对门静脉高压性胃病的影响
Impact of different endoscopic esophageal varices treatment on portal hypertensive gastropathy
吴巍 1王立夫 1陶凤来 1徐贝黎 1叶佩君 1陈舒 1袁耀宗1
作者信息
- 1. 上海交通大学医学院附属瑞金医院消化科,上海 200025
- 折叠
摘要
Abstract
Objective: To analyze the impact of different endoscopic esophageal varices treatment on severity of portal hypertensive gastropathy (PHG). Methods: A total of 35 patients with endoscopic treatment of esophageal varices at Department of Gastroenterology, Shanghai Ruijin Hospital from January 2015 to March 2016 were enrolled. Either endoscopic injection sclerotherapy (EIS) or varices ligation (EVL) was performed, and the concomitant gastric varices, if present, was treated with tissue adhesive obturation (GVO). Additional endoscopic treatment was performed when necessary and patients were followed up for PHG evaluation. Results: Seventeen patients received EIS and 18 received EVL at the initial endoscopy. During follow-up, 16 and 13 patients of the above mentioned groups, respectively, remained in the same group, while the other 6 patients turned to receive a mixed therapy of EIS and EVL because of either technical failure, inadequate regression after EIS or residue varices not suitable for another EVL. Mean endoscopic follow-up was (8.6±4.0) months. Patients with severe, mild and absent of PHG were 0, 18, 17 at baseline and 3, 16, 16 at last follow-up, respectively (P>0.05). EVL and mixed therapy were seemed to be superior to EIS in both long-term hemostasis and PHG stability. The average Child-Pugh scores at baseline and last follow-up were (6.77± 1.73) and (6.00±0.91), respectively, indicating that endoscopic treatment was beneficial to liver function improvement (P<0.01). Conclusions: Endoscopic treatment for esophageal varices would not have significant negative influence on PHG.关键词
门静脉高压性胃病/静脉曲张/内镜/内镜下静脉曲张套扎术/内镜下硬化剂注射治疗Key words
Portal hypertensive gastropathy/Varices/Endoscopy/Endoscopic varix ligation/Endoscopic injection sclerotherapy分类
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吴巍,王立夫,陶凤来,徐贝黎,叶佩君,陈舒,袁耀宗..不同食管静脉曲张内镜治疗方法对门静脉高压性胃病的影响[J].诊断学理论与实践,2016,15(5):464-467,4.