中国美容医学2016，Vol.25Issue(10)：76-79,4.
HMME-PDT联合氟制剂预防龋病的动物实验研究
Animal experimental study of HMME-PDT combined with lfuoride to prevent dental caries
摘要
Abstract
Objective To observe the effect of hmme-pdt combined with lfuoride to prevent dental caries in animal model, Based on the construction of dental caries. Methods Select 21d weaning SPF-Wista rats 80, the planting of Streptococcus mutans to construct cariogenic model is divided into distilled water, hmme-pdt, sodium lfuoride, and hmme-pdt+sodium lfuoride group 4 groups, continuous 8W to rats by oral treatment collected rat saliva culture, record deformation levels of Streptococcus and observe the experimental group rats in the mouth of the deformation of the streptococcal growth effects on the reproductive and assessment scores of Keyes inhibitory effect on the formation of dental caries. Results Compared with the distilled water group and other groups deformation streptococci levels and dental caries Keyes scores showed different degrees of reduced the hmme-pdt display of pit and ifssure caries and smooth surface caries has better control effect (P<0.05), but lower than that of the sodium lfuoride group;hmme-pdt+sodium lfuoride group has no obvious synergistic inhibitory effect on caries. Conclusion HMME-PDT can effectively inhibit oral Streptococcus mutans reproduction and reduction in the caries incidence.关键词
龋病/HMME-PDT/动物模型/变形链球菌/氟制剂Key words
caries/HMME-PDT/animal model/Streptococcus mutans/lfuoride分类
医药卫生引用本文复制引用
牛巧丽,孙玉亮,努尔比亚木·麦麦提依明,赵今..HMME-PDT联合氟制剂预防龋病的动物实验研究[J].中国美容医学,2016,25(10):76-79,4.基金项目
新疆医科大学第一附属医院院内科研项目资助（自然科学基金青年项目）(2013ZRQN31) （2013ZRQN31）
