中国药理学通报2016，Vol.32Issue(11)：1481-1485,1486,6.DOI:10.3969/j.issn.1001-1978.2016.11.001
鸦胆子苦木内酯类成分及其药理活性研究进展
The research progress of quassinoids components in Brucea javanica and their pharmacological activities
摘要
Abstract
Fructus Bruceae, the dry and ripe fruits of Brucea ja-vanica( L. ) Merr. ( Simaroubaceae) , has been used for dysenter-y, tumor, malaria and furunculosis treatment, and topical appli-cation for warts and corns. Quassinoids are the main chemical constituents of Fructus Bruceae, which have been proved to have anti-tumor, anti-inflammatory, insecticidal, anti-viral, anti-bac-terial and hypoglycemic activities, and so on. In view of the ex-tensive pharmacological activities of Fructus Bruceae, and better development and utilization of its medicinal value, the advances of quassinoids in Fructus Bruceae and their pharmacological ac-tivities are reviewed in this paper.关键词
鸦胆子/苦木内酯类成分/药理活性/抗肿瘤/抗炎/研究进展Key words
Brucea javanica L. Merr/quassinoids/pharmacolog-ical activities/anti-tumor/anti-inflammation/research progress分类
医药卫生引用本文复制引用
傅丽霞,黄崇刚,林明宝,侯琦..鸦胆子苦木内酯类成分及其药理活性研究进展[J].中国药理学通报,2016,32(11):1481-1485,1486,6.基金项目
国家自然科学基金资助项目( No 81473398) （ No 81473398）
协和青年基金项目(No 3332015163) （No 3332015163）
天然药物活性物质与功能国家重点实验室开放课题(No GTZK201407,GTZK201613) （No GTZK201407,GTZK201613）
