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急性肾损伤的分子机制及中药干预研究进展

尹连红 齐蒙 彭金咏

中国药理学通报2016,Vol.32Issue(11):1494-1499,1500,7.
中国药理学通报2016,Vol.32Issue(11):1494-1499,1500,7.DOI:10.3969/j.issn.1001-1978.2016.11.004

急性肾损伤的分子机制及中药干预研究进展

Molecular mechanism of acute kidney injury and intervention by Chinese medicine

尹连红 1齐蒙 1彭金咏1

作者信息

  • 1. 大连医科大学药学院,辽宁 大连 116044
  • 折叠

摘要

Abstract

Acute kidney injury (AKI), a common clinical dis-ease, is one complex pathophysiological process. In this review paper, the relationship and the molecular mechanisms of ische-mia-reperfusion, major surgery, rhabdomyolysis, pus sepsis and drug-induced renal toxicity associated with AKI were comprehen-sively reviewed. In addition, the prevention and treatment of AKI by Chinese medicine and the effective components were also reviewed. Therefore, our review aims to provide valuable infor-mation for treatment of AKI, and also for exploration of innova-tive new drugs.

关键词

急性肾损伤/缺血/再灌注/发病机制/中药/天然产物/预防和治疗

Key words

acute kidney injury/ischemia/reperfusion/patho-genesis/traditional Chinese medicine/natural product/preven-tion and treatment

分类

医药卫生

引用本文复制引用

尹连红,齐蒙,彭金咏..急性肾损伤的分子机制及中药干预研究进展[J].中国药理学通报,2016,32(11):1494-1499,1500,7.

基金项目

国家自然科学基金资助项目( No 81274195) ( No 81274195)

辽宁省百千万人才资助项目(No 2015-065) (No 2015-065)

中国药理学通报

OA北大核心CSCDCSTPCD

1001-1978

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