中国药理学通报2016,Vol.32Issue(11):1500-1504,1505,6.DOI:10.3969/j.issn.1001-1978.2016.11.005
瞬时感受器电位通道在肿瘤增殖与迁移中的作用
Role of transient receptor potential channels in proliferation and migration of cancer
摘要
Abstract
The transient receptor potential( TRP) subfamilies be-long to the non-selective cation channels located at cell mem-branes. Calcium across the plasma membrane into the cell via most TRP channels may result in localized Ca2+ signals that con-tribute to cell proliferation, migration and metastasis. In recent years, many studies have focused on the role of TRP in cancer. This review intends to gather the latest progress concerning TRP channels on proliferation and migration of cancer.关键词
瞬时感受器电位/钙通道/肿瘤/增殖/迁移/转移Key words
transient receptor potential/calcium channel/canc-er/proliferation/migration/metastasis分类
医药卫生引用本文复制引用
林达岑,林默君,周瑞祥..瞬时感受器电位通道在肿瘤增殖与迁移中的作用[J].中国药理学通报,2016,32(11):1500-1504,1505,6.基金项目
国家自然科学基金资助项目(No 30971541,31571179) (No 30971541,31571179)
福建省自然科学基金资助项目(No 2015J01313) (No 2015J01313)
福建医科大学重点项目(No 09ZD018) (No 09ZD018)