中国中西医结合外科杂志2016，Vol.22Issue(5)：419-423,5.DOI:10.3969/j.issn.1007-6948.2016.05.001
影响老年胰腺癌预后的多因素分析
Multple Factors Analysis of Elderly Patients with Pancreatic Carcinomas
魏志旺 1李强2
作者信息
- 1. 天津医科大学肿瘤医院，国家肿瘤临床医学研究中心，天津市“肿瘤防治”重点实验室，天津市恶性肿瘤临床医学研究中心 天津 300060
- 2. 天津医科大学总医院普通外科 天津300052
- 折叠
摘要
Abstract
Objective To explore the major prognostic factors in old patients with pancreatic carcinoma. Methods One hundred and twenty-one patients with pancreatic carcinoma from 2004 to 2012 choosed from Tianjin Medical University Cancer Hospital were reviewed. Survival rate was caculated by Kaplan-Meier estima⁃tion while survival curve was analysed by log-rank test. Prognostic factors were studied by multivariate analysis with COX proportional hazards survival model. Results In this group, the survival time was 1 to 19 months and the median survival time was (6.0 ± 2.3) months. The overall survival rates at 6 months, 12 months, 18 months were 51.2%, 13.3%, and 4.1% respectively. Multivariate analysis revealed that independent prognostic factors were TNM tumor staging, sugical mode, chemotherapy, symptomatic and supportive therapy. Conclusion Elderly patients with pancreatic cancers always have poor ability for tolerance with surgery, radiation and che⁃motherapy. Becasuse of various reasons, they were not suitable to conventional treatment. They should be individ⁃ually treated according to the conditions of the elderly individual. The ultimate aim was to offer a radical cure as much as possible under the premise of prolonging the survival time and improving the quality of life.关键词
老年胰腺癌/COX比例风险模型/预后Key words
Elderly patients with pancreatic carcinoma/COX proportional hazards survival model/prognosis分类
医药卫生引用本文复制引用
魏志旺,李强..影响老年胰腺癌预后的多因素分析[J].中国中西医结合外科杂志,2016,22(5):419-423,5.
