中华临床免疫和变态反应杂志2016，Vol.10Issue(3)：191-196,6.DOI:10.3969/j.issn.1673-8705.2016.03.002
门诊患者食物诱发严重过敏反应的病因及临床特征
Clinical Characteristics and Aetiologyic Factors of Food-Induced Anaphylaxis among Outpatients
王子熹 1韩伟 1李宏 1尹佳1
作者信息
- 1. 中国医学科学院 北京协和医学院 北京协和医院变态 过敏 反应科，北京100730
- 折叠
摘要
Abstract
Objective To investigate the clinical characteristics and aetiologyic factors of food-induced anaphylaxis among Chinese outpatients.Methods Medical records of outpatients who were diagnosed as anaphylaxis were collected from Department of Allergy, Peking Union Medical College Hospital since June 18th, 2008 to July 1st, 2012. The allergenic foods and other clinical characters were analyzed retrospectively.Results 170 patients were diagnosed as anaphylaxis during the period mentioned above, 97 of them were involved in this study whose medical records were stored in PUMC hospital.77 patients were diagnosed as food-induced anaphylaxis, whose average age was 28 ( 13 to 61 ) years-old.Patients were divided into adolescent (13-17 years-old) and adult ( above 18 years-old) group.Allergenic foods could be identified among 89.6% of patients.Wheat ( 53.2%) was the most common allergenic food among all patients, whereas vegetables/fruits ( 57.1% vs.26.8%) and legume/peanut ( 52.4% vs. 21.4%) were more common among adolescents compare to adults group ( P<0.05) .Percentage of pollen sensitization was significantly higher in the adolescents group ( 71.4% vs.32.1%, P <0.05 ) compare to adults group.Cutaneous symptoms were the most common (80.5%) clinical manifestation, followed by respiratory symptoms ( 57.1%) .Among the patients with wheat-induced anaphylaxis, the percentage of exercise-induced was significantly higher ( 31.7%, P<0.05 ) compare to patients whose anaphylaxis were induced by the other kinds of foods.Chronic urticaria/dermatitis seemed to be the risk factors for developing life-threatening anaphylaxis (29.5%vs.9.1%, P<0.05).Conclusion In our study, wheat was the most common allergenic food among all outpatients, and often induced by exercise. Cutaneous symptoms were the most common symptoms.Vegetables, fruits, legume and peanut should be aware of potential allergenic foods for food-induced anaphylaxis among hay fever adolescent patients.High risk for life-threatening anaphylaxis should be conscious of anaphylaxis patients with chronic urticaria/dermatitis.关键词
严重过敏反应/食物过敏/门诊患者Key words
anaphylaxis/food allergy/outpatients引用本文复制引用
王子熹,韩伟,李宏,尹佳..门诊患者食物诱发严重过敏反应的病因及临床特征[J].中华临床免疫和变态反应杂志,2016,10(3):191-196,6.
