中华临床免疫和变态反应杂志2016,Vol.10Issue(3):269-275,7.DOI:10.3969/j.issn.1673-8705.2016.03.015
严重过敏反应的加重因素及作用机制
Trigger Factors and Mechanism of Anaphylaxis
姜楠楠 1尹佳1
作者信息
- 1. 中国医学科学院 北京协和医学院 北京协和医院变态 过敏 反应科,北京100730
- 折叠
摘要
Abstract
Anaphylaxis is a rapid-onset, severe, even life-threaten systemic reaction mediated by type I allergic reaction.Many factors can aggravate the severity of anaphylaxis, which is called trigger factors or co-factors. Some kinds of medicines such as non-steroidal anti-inflammatory drugs ( NSAID) and concomitant infectious diseases are well-documented co-factors of anaphylaxis besides physical exercises or alcohol consumption. Co-factors involve in about 30%of anaphylactic reactions.The underlying mechanisms that co-factors aggravate the severity of anaphylaxis include increasing of bioavailability of allergens and decreasing of cell activation threshold.关键词
严重过敏反应/机制Key words
anaphylaxis/mechanism分类
医药卫生引用本文复制引用
姜楠楠,尹佳..严重过敏反应的加重因素及作用机制[J].中华临床免疫和变态反应杂志,2016,10(3):269-275,7.