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严重过敏反应的加重因素及作用机制

姜楠楠 尹佳

中华临床免疫和变态反应杂志2016,Vol.10Issue(3):269-275,7.
中华临床免疫和变态反应杂志2016,Vol.10Issue(3):269-275,7.DOI:10.3969/j.issn.1673-8705.2016.03.015

严重过敏反应的加重因素及作用机制

Trigger Factors and Mechanism of Anaphylaxis

姜楠楠 1尹佳1

作者信息

  • 1. 中国医学科学院 北京协和医学院 北京协和医院变态 过敏 反应科,北京100730
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摘要

Abstract

Anaphylaxis is a rapid-onset, severe, even life-threaten systemic reaction mediated by type I allergic reaction.Many factors can aggravate the severity of anaphylaxis, which is called trigger factors or co-factors. Some kinds of medicines such as non-steroidal anti-inflammatory drugs ( NSAID) and concomitant infectious diseases are well-documented co-factors of anaphylaxis besides physical exercises or alcohol consumption. Co-factors involve in about 30%of anaphylactic reactions.The underlying mechanisms that co-factors aggravate the severity of anaphylaxis include increasing of bioavailability of allergens and decreasing of cell activation threshold.

关键词

严重过敏反应/机制

Key words

anaphylaxis/mechanism

分类

医药卫生

引用本文复制引用

姜楠楠,尹佳..严重过敏反应的加重因素及作用机制[J].中华临床免疫和变态反应杂志,2016,10(3):269-275,7.

中华临床免疫和变态反应杂志

OACSTPCD

1673-8705

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