检验医学与临床2016，Vol.13Issue(22)：3138-3140,3.DOI:10.3969/j.issn.1672-9455.2016.22.003
莫西沙星对多重耐药肺结核患者血清降钙素原和sT REM-1水平的影响
The influence of moxifloxacin on serum levels of PCT and sTREM-1 in patients with multiple drug resistance tuberculosis
摘要
Abstract
Objective To evaluate the influence of moxifloxacin on serum levels of procalcitonin (PCT ) and sTREM‐1 in pa‐tients with multiple drug resistance tuberculosis (MDR‐TB) .Methods One hundred and eighty patients with MDR‐TB were en‐rolled in this study and randomly divided into two group :moxifloxacin group and control group .The levels of PCT and sTREM‐1 were under dynamic observation in three time points (before the treatment ,2 months and 6 months after treatment ) .Correlation a‐nalysis was used to estimate the association between moxifloxasin and changes of PCT and sTREM ‐1 .Results The accumulative curative effect rate of moxifloxacin group (85 .6% ) was significantly higher than that of the control group (70 .0% )(P < 0 .05) . The levels of PCT and sTREM‐1 were significantly lower than before the treatment in moxifloxicin group .And the levels of PCT and sTREM‐1 of 2 months and 6 months after the treatment were significantly lower than that in control group (P< 0 .05) .Conclu‐sion Moxifloxacin can effectively control the MDR‐TB and decrease the serum levels of PCT and sTREM‐1 .关键词
莫西沙星/多重耐药肺结核/降钙素原/可溶性髓系细胞触发受体-1Key words
moxifloxaxinl/multiple drug resistance tuberculosis/procalcitonin/sTREM-1引用本文复制引用
林嘉..莫西沙星对多重耐药肺结核患者血清降钙素原和sT REM-1水平的影响[J].检验医学与临床,2016,13(22):3138-3140,3.基金项目
四川省卫生厅资助项目（09461）。 （）
