摘要
Abstract
Objective To investigate ultrasound echogram and pathologic characteristics of benign thyroid nodules misdiagnosed as thyroid carcinoma by ultrasonography. Methods Clinical data of preoperative ultrasound echogram and post-operative pathologic examination of 70 patients (86 nodules) with benign thyroid nodules misdiagnosed as having thyroid carci-noma by ultrasonography from 2012 to 2015 was retrospectively analyzed. Results Among the 86 misdiagnosed nodules, pre-operative ultrasonographic characteristics were very low echo-level (80. 23%), irregularity edge (58. 14%), vertical and horizontal diameter ratio less than or equal to 1 (69. 77%), calcification (77. 91%), cystic and solid (86. 05%), nodule diameter more than 10 mm (52. 33%) and main TIRADS classification with 4a-4c (88. 37%). Postoperative pathological ex-amination showed nodular goiter in 62 cases (88. 57%), atypical adenoma of thyroid gland in 6 cases (8. 57%) and subacute thyroiditis in 2 cases (2. 86%). Mainly pathological characteristics were extensive fibrosis associated by vitreous degeneration in 72 cases (83. 72%), calcification in 57 cases (66. 28%), hemosiderin in 19 cases (22. 09%), enriched gloea in 13 ca-ses (15. 12%), inflammatory cells infiltration in 7 cases (8. 14%), osseous metaplasia in 3 cases (3. 49%), remote hemor-rhage in 2 cases (2. 33%) and epithelial squamous metaplasia in 2 cases (2. 33%). Conclusion Vitreous degeneration and calcification of pathological characteristics in patients with benign thyroid nodules are easily misdiagnosed as having malignant thyroid nodules by ultrasound examination, and therefore clinicians should comprehensively diagnose combined with pathologi-cal and other examinations.关键词
甲状腺疾病/超声/误诊/甲状腺肿瘤Key words
Thyroid diseases/Ultrasound/Misdiagnosis/Thyroid neoplasms分类
医药卫生
